Dr. Moon-Keen LEE

Consultant Neurologist and Movement Disorders Specialist

http://mkleeneuro.com

MBBS (Malaya), Dip Clinical Neurology (London), FRCP (Edinburgh), Fellow, Academy of Medicine, Malaysia

Dr Lee Moon Keen is a Consultant Neurologist who was trained at the University of Malaya and later at the Institute of Neurology, University of London, through the Chevening Scholarship of the British High Commission.  After leaving an academic position at University Hospital Kuala Lumpur, she commenced private practice in 1994.

Dr Lee’s main interest is in Movement Disorders, including Parkinson’s disease.  She is Director of the Sunmed Functional Surgery Team which performed the first Parkinson’s Surgery operation for Deep Brain Stimulation (DBS) in Malaysia in 2003.  The team continues to publish in this subspecialty area and is looking into future directions such as stem cell research.  She is serving as Review Editor for the journal Frontiers in Neurorestoratology http://frontiersin.org/neuroscience/neurorestoratology/editorialboard/.

Dr Lee is a Founder Member of the Malaysian Society of Neurosciences and has served as Vice-President.

As a Fellow of the Academy of Medicine of Malaysia, Dr Lee is a member of the Neurology Credentialling Committee for the National Specialist Register.  She has served on the Subcommittee for Strategic Planning as well as various expert committees for drafting Clinical Practice Guidelines on Parkinson’s Disease, Stroke and Brain Death Certification.  For the Malaysian Medical Council, she worked with the committee which drafted the Council’s guide on Good Medical Practice.

Interview on Epilepsy on Radio BFM


  1. Misel
    24 March, 2016 at 1:58 PM

    Dear Dr Lee

    I would like to seek for your kind advise and a second opinion.

    My dad age 62, he is active sport man – badminton player and jogging regularly.
    On 14 March 2016 (Monday), my dad unwell, feeling giddiness and a little nausea during noon time, but feeling tired and a little weak, hence my dad take rest and nap, and only went hospital to see GP evening 7pm. Being prescribed 1 x amlodipine and anti vertigo medicine as doctor mentioned is high blood (168/90). But my dad medical history does not have high blood pressure. Dad been resting at home few days. Till 17 March 2016 (Thursday), which alert us when we brought dad out for dinner in a restaurant which we have been before, but he cannot remember this place, seem memory lapse. The next day 18 March (Friday), we brought dad visit his regular cardiologist as dad has AF since 2010, he been taking cordarone (100mg) and cardirpirin (100mg), taken daily since then. Cardio recommended dad for MRI and MRA test.

    Report on 18 March (Friday) showed conclusion :-
    1) Acute infarcts demonstrated in the left temporo-occipital lobe in posterior cerebral artery territory and minimally in the right thalamus and right occipital lobe.
    2. No stenosis demonstrated in the MRA.

    We went for neurologist on 21 March (Monday), did blood test. No medication prescribed at the moment, hence dad only take back his usual cardiprin and cordarone.
    Next day 22 March (Tuesday), blood test result highlight;
    1. thyroid stimulating hormone *7.26, free T3 (4.0) and free T4 (11.1)
    2. renal function – estimated – GFR (CKD-EPI) : 77
    3. Total cholesterol 5.4

    Dad being prescribed Xarelro (to replace cardiprin) and thyroidine medicine for 1 month.

    Dr Lee, I have some queries still:
    1) Sometimes my dad cannot really remember direction/places we have been, seems like dejavoo for him, is the blood clot in the brain affected the memory part?
    2) Can Xarelto help dissolve the blood clot in brain?
    3) Can dad still do some exercise? is it good for him? as he feel tired easily, is it because of the blood clot in the brain?
    4) May I know the different between Eliquis vs Xarelto?
    5) if there is any small cut (ie. shaving) , need to go hospital immediately? afraid bleeding too much.

    Thank you Dr Lee, hope to hear from your kind advise.

    • 30 March, 2016 at 2:05 PM

      Dear M Tham

      Your father’s condition needs detailed knowledge of his complex clinical situation in order to formulate any meaningful advice. His doctor is in possession of all the clinical information and therefore would be in the best position to provide the answers to your queries, including the rationale for choice of medication, and medication-related issues.

      Best wishes,

      Dr Lee Moon Keen

  2. valerie
    19 October, 2015 at 11:24 PM

    Hi Dr Lee,
    Eight months ago, my dad’s blood pressure shot up above 170 systolic which he does not has a history of high blood. The MRI showed Ischemic Brain Changes. At the same time, he has severe hallucinations and affecting his behavior . Subsequently, he was diagnosed for Sleep Apnea. Since then, he has been using the CPAP machine. He is now taking 3 types of medication. (High blood pills, Clonotril and Scroquel). The hallucinations is under control . 2 weeks ago, he complained that the medication makes him so tired and I observed that his memory deteriorated fast. I am not sure if its due to the medication or something else.
    It’s so heartbreaking to see my dad suffering from this condition. He is seeing a neurologist and I truly need a second opinion.
    Hope to hear from you ASAP and thanks in advance.

    • 22 October, 2015 at 7:57 AM

      Dear Valerie

      Thank you for your enquiry. Your father has a complex set of symptoms which requires a thorough evaluation of his clinical status and test results.

      Do contact a neurologist for reassessment.

      Best wishes,

      Webmaster

  3. Lee Choon Ling
    7 August, 2015 at 12:27 PM

    Hi Dr Lee,

    My sis is having loss of concentration, memory and ability to understand well. Kindly advise what doctor she should consult & what she should do. She is only 32 years old.

    TQVM for your valuable advise.

    Natasha Lee

    • 11 August, 2015 at 11:07 PM

      Dear Natasha

      Your sister has been given a response directed to her personal email.

      Best.

  4. Metty
    1 August, 2015 at 11:04 AM

    Replied

    Salam dr.lee…
    Suami saya umur 38 tahun pernah terkena benturan dikepala bagian belakang.setelah ctscan tidak ada masalah. Bbrp tahun kemudian merasakan kram ditangan jari kesemutan sampai naik dilengan dibagian kanan dan kadang gemetar seperri orang termos .dokter menyatakan dia terkena parkinson lalu diberi aekine tapi reksinyabelum ada.lalu ditambah stalevo dan sifrol kondisi membaik.tetapi kalau telat minum obat atau tidak minum obat akan kaku lalu tiba2 mengeluarkan gerakan yang kadang sulit untukdikendalikan.sekarang sudah dirasakan diseluruh badan sampai merasakan sakit dikepala bagian belakang hingga kw batang leher. Pengobatan apa yang sebaiknya dilakukan? Terima kasih.

    • 22 October, 2015 at 8:10 AM

      Hi Puan Metty

      Maaf dipohon kerana lewat menjawab. Email Puan telah dikurung dalam spam filter.
      Ciri-ciri suami Puan memang konsisten dengan penyakit Parkinson. Selepas suatu masa mengambil rawatan Parkinson, akan muncul komplikasi Motor Fluctuation dan Dyskinesia. Oleh yang demikian, ubat-ubat perlu diubahsuaikan. Antara ubat yang membantu adalah Sifrol dan Amantadine. Ada pihak di Jepun yang mengesyorkan Zonisamide dalam dos yang rendah.

      Bagi kes yang rumit, pengisian Deep Brain Stimulator melalui pembedahan otak mungkin diperlukan.

      Salam hormat.

      Dr Lee

  5. Cheng Soon
    3 December, 2013 at 10:45 AM

    Dear Dr Lee,

    My father, age 66. He did an EMG recently with this comment:

    The sensory responses are small but present in both upper and lower limbs. The median CMAP amplitudes are smaller on the right. Needle EMG show chronic denervation changes in the R and L proximal and distal upper limb muscle.

    The findings may be consistent with diffuse anterior horn cell disease.

    What does above findings indicate? Dr KJ Goh (UMSC) commented most likely is Motor Neuron Disease. However, he suggested several bloodtest to rule out other possibilities. Now still pending for the bloodtest result. However, Dr Goh recommend my father to start physiotherapy.

    Based on above findings, what do you think? does my father need to go for more test to confirm the diagnosis? How severe is his condition based on above findings?

    Looking forward to your reply Dr Lee.

    Regards,
    Cheng Soon
    (email: chengsoon.teoh@yahoo.com)

    • 4 December, 2013 at 5:38 PM

      Dear Cheng Soon

      It looks like your father is receiving appropriate and comprehensive assessment and clinical testing. It is best that you discuss the results and next steps with his neuro consultant.

      All the best.

      Dr M K Lee
      Consultant Neurologist

  6. RG
    7 November, 2013 at 1:43 PM

    As advised by Dr Lee, many of the questions here can be best attended to by making an appointment to see a Neurologist, This is because the complexity of the human body system as well as history & clinical examination is required.
    Please contact the clinic (see Contact Us) for an appointment.

  7. Sally tan
    29 July, 2013 at 1:25 PM

    Dear Dr. Lee

    I am having problem of numbness on my hand for the past ten years, recently getting worse, it goes to my leg as well, normally the numbness would move around, sometime in right hand and sometime in left hand, and all the time I have lower back bone pain, I can’t side sleep for more than 10 minutes, and I noticed that when I have any exercise which need to use strength on the neck and lower back bone, my numbness would get bad and would feel it immediately. However, for the past ten years, I went to see many doctors, it includes traditional chinese doctors, neurosurgeon, cardiologist and orthopaedic, they all said nothing wrong to me. Neurosurgeon check on my reaction of my leg and said it is abnormal and it could be “spurs” problem. However, after the MRI report out, it shows no “spurs” on my neck and lower back bone, but when I went to see two chinese traditional doctors, they all claims that I have spurs on my neck and lower back bone. So, Dr. Lee could you please advise me what is my actual problem? could it be these numbness problem was due to in year 2000 I did fell down from the staircase and caused the side effect? should I refer my case to spine specialist? Below are my past ten years X-Ray and MRI reports findings and comments for your attention.

    Year 1999 – CT Scan of Lumbar Intervertebral Disc L3 – S1 = no obvious PID seen at all levels. No osteophytosis. No evidence of spinal stenosis seen.

    Year 2000 – Lumbosacral spine = mild scoliosis to the right? Significance (after fell down from the staircase).

    Year 2004 – MRI Cervical Spine at Sunway Medical Centre, but no report, assume everything are fine ???

    Year 2011 – MRI Cervical Spine at UM specialist Hospital = Image quality degraded by motion artifact.
    The cervical alignment appears normal.
    The Cervico – medullary junction is normal.
    The Cord returns normal signed.
    The exit foraminae are normal.
    The Carotid vessels normal.
    The R vertebral is smaller and appear to enter the foramen transversum at higher level.

    At the same time, I have EMG report comments that : Nerve conduction studies and needle EMG are within normal limits.

    Thank you.

    Best Regards

    Sally Tan

    • 31 July, 2013 at 4:03 PM

      Dear Ms Tan

      Thank you for your enquiry. Your history is not straightforward and there are many imaging studies to consider. Based on the info given, it is not possible to give any recommendation. As such, I would advise that you see a specialist in person, in order to have a detailed consultation and clinical assessment.

      Best wishes.

  8. Koo Lily
    25 February, 2013 at 10:15 AM

    Thanks a lot! Clearer now for what to do next…
    Lily

  9. Koo Lily
    24 February, 2013 at 5:28 PM

    Dear Dr Lee,

    My dad aged 75 has just been diagnosed with Motor Neuron Disease, onset happened 1-2 months ago when he started to have hand numbness, pain, and now he cannot lift his left arm for daly chores. It was shocked to us to hear he has MND, and I know it it critical? We would like to seek second opinion from you to confirm his disease. Other than that, what should we do for now? Thanks, and hope you can help.

    Lily

    • 25 February, 2013 at 9:47 AM

      Dear Ms Koo, we are happy to study your father’s case and discuss his diagnosis, whether or not it is Motor Neuron Disease, and what are the available options. Please get in touch with my clinic staff if a consultation is desired.

      Best regards.

      Dr M K Lee

      • Koo Lily
        25 February, 2013 at 9:59 AM

        Dear Dr Lee,
        THANKs so much for your swift response. I wonder if seeking a neurologist second opinion is the next step forward, or it involves speciality from other faculty, e.g. cardiologist (he started with pain and num on his left arm, and now his left arm is cannot perform any daily job, e.g. buttoning etc) for possibilyt of stroke….etc. May i scan his report to you for a quick view to determine if neurologist is the next step, or others?
        Thanks so much again!
        Lily

      • 25 February, 2013 at 10:09 AM

        Dear Ms Koo

        It is not likely to be other than neurological problem from your story. Please consult the neurologist.

        Best.

  10. 12 September, 2012 at 3:43 PM

    Dear Pei Shi

    Dizziness is not a feature of myasthenia. Perhaps after all these years, the diagnosis needs to be reassessed. Your psychiatrist would have recommended treatment for depression based on standard diagnostic criteria, hence this should be followed. So it remains to be established whether your mother still has myasthenia or she has recovered from it. A neurological consultation should settle this issue.

    All the best.

    Dr Lee Moon Keen
    Consultant Neurologist

    • Pei Shi
      12 September, 2012 at 4:58 PM

      Dear Dr Lee,
      Thank you for your valuable advice,I would like to ask doctor a few question : —
      1) MYASTHENIA disease will be fully recovered? It can be tested out?
      2) For my mother’s dizziness, can Dr Lee recommend a doctor consultant for dizziness in Sunway Medical Centre? Or can Dr Lee suggest which doctor should my mother look at ?

      Thanks & Regards,

      Pei Shi

  11. ethan
    23 July, 2012 at 2:24 AM

    Hi Doctor Lee. My name is Ethan and I am 24 years old undergraduate. I am facing symptoms like migraine, extremities numbness, neck pain, chest pain, stiff shoulder and arm pain since year 2011. Been undergo a MRI check in September 2011 which reported central disc bulge at C3/4 & mild disc bulges at C4/5 and C5/6. Signal intensity in the spinal cord is normal.
    Medication prescribed by my specialist doctor were imigran, propanolol, sibelium and arcoxia. However, these medication doesn’t really work on me, except Arcoxia. However, I have been stop taking Arcoxia since November 2011.
    My doctor told me that I do not require a surgery treatment, and symptoms occurs due to the narrow space movement between the cervical disc.
    But due to the pain persists afterwards. I look for physical treatment such as acupuncture, massage and even chiropractor. And I have been spending thousand over Ringgit for all kind of physical treatment. However, those treatments could only help to relieve my pain and don’t seem to give much help on the overall condition.
    These days, the numbness feeling around my extremities get worsen and occur quite frequently. Shoulder stiffness also exaggerating. I can’t sleep well with a pillow and thus I end up not using any. I wonder is my slipped disc problem worsen? Should I go for another MRI check though the last time I did was half year ago?
    Or should I continue to take Arcoxia 120mg? Would it be any hindered side effects?
    What would Dr. Lee recommend? I would appreciate if you could give some advice about it. Thank you very much!

    • 23 July, 2012 at 9:41 AM

      Dear Ethan, you need to explore with your specialist what degree of the symptoms is due to contribution from migraine. Thereafter, do assess whether they might be arising from stress and overuse. Fitness level and poor postural habits need to be considered. All the best.

      • ethan
        23 July, 2012 at 12:48 PM

        Hi Dr, Lee,
        Thank you for your advice..
        by the way, i have also a MRI check on my brain, there is no any damage results observed.
        My neurosurgeon suggest migraine probably due to the slipped disc problem. Because I always encounter neck pain before migraine attacked.

        Anyway Dr Lee, should I refer my case to a neurosurgeon or orthopaedic surgeon?

        Thank you!

  1. 3 August, 2010 at 7:32 PM

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